Despite the controversy, its abundantly clear is that hydroquinone is a wellresearched ingredient, incredibly effective for its intended purpose, and that no other skin lightening ingredient compares to its effectiveness. Material safety data sheet tertiary butylhydroquinonetbhq msds. This compound is a generalpurpose inhibitor, stabilizer, antioxidant, and intermediate. Hydroquinone, also known as benzene1, 4diol, is an aromatic organic compound which is a type of phenol, having the chemical formula c6h4oh2. Amended safety assessment of hydroquinone as used in.
If inhaled if breathed in, move person into fresh air. Eleven out of 22 samples were found to contain hydroquinone. It is used in photographic, chemical and cosmetic industries. It may be found in concentrations up to 15% or more but a doctors prescription is required by the fda united states for. Hydroquinone is a white to light colored crystalline sandlike solid. May cause dizziness, nausea, sense of suffocation, increased respiratory rate, vomiting, pallor, muscle twitching, cyanosis bluish discoloration of skin due to deficient oxygenation of the blood, delirium. Qualitative and quantitative estimation of hydroquinone in. Prescription strength preparations are available in higher concentrations up to 4%. Find msds or sds, a coa, data sheets and more information.
Pure culture oxidation of hydroquinone produced 1,4benzoquinone, 2hydroxy1,4benzoquinone and betaketoadipic acid5. Hydroquinone msds 822333 milliporesigma emd millipore. Substituted derivatives of this parent compound are also. It can lighten everything from freckles and acne scars to postinflammatory marks caused by conditions. Material safety data sheet tertiary butylhydroquinonetbhq. Overthecounter otc skin lightening products usually contain 2% hydroquinone. In the presence of air and moisture, hydroquinone dust may react to form irritating quinone which forms a vapor at room temperature. P202 do not handle until all safety precautions have been read and understood. May cause severe irritation of the digestive tract. Pure hydroquinone does not readily form a vapor at room temperature. Occupational exposure to hydroquinone may occur by inhalation or dermal contact, especially in those who develop black and white film, since hydroquinone is a common component of developing solutions hsdb, 2005d. Safety data sheet creation date 26sep2009 revision date 18jan2018 revision number 4 1. The most complete free material safety data sheet msds list.
Hydroquinone, usp hydroquinone, usp sds preparation date 10172016. Read the product manufacturers material safety data sheet msds and the label to determine product. In case of skin contact wash off with soap and plenty of water. An amended safety assessment of hydroquinone alone was published with the conclusion that hydroquinone was safe at concentrations of 1. Safety data sheet according to federal register vol. Tinnitus ringing in the ears, dizziness, headache, nausea, vomiting, dyspnea, erosion of the gastric. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Hydroquinone, usp is an effective topical medicine used to treat dark colored patches, freckles, and spots on the skin that appear due to sun exposure. Hydroquinone, also known as benzene1,4diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula c 6 h 4 oh 2. The hplc analysis showed the concentration of hydroquinone ranged from 0. Extrasynthese is a leading chemicals company that provides customers with highquality hydroquinone standard reference material. Amended safety assessment of hydroquinone as used in cosmetics.
Our msds database is an easy to use, do it yourself tool, and best of all. Safety data sheet according to regulation ec no 19072006 page 1 of 12 loctite 401 sds no. It is used in developers for photography and lithography. Hydroquinone safety data sheet according to federal register vol. Sewage sludge activated to phenol was found to oxidize hydroquinone 3,4. This staining is temporary and can typically be removed with soap and water washing, but its best to avoid benzoyl peroxide. Subscribe to our newsletter to keep up to date on our latest flavors and fragrances offerings.
Wear appropriate protective eyeglasses or chemical safety goggles as described by whmis or oshas eye and face protection regulations in 29 cfr 1910. Material safety data sheets sds msds material safety data sheets sds msds are available by using hpc standards catalog numbers to search for products. Hydroquinone is used as a developing agent in photography and as an antioxidant in rubber and food. Material safety data sheet eastman chemical company. Get medical adviceattention p310 immediately call a poison centerdoctor p330 if swallowed, rinse mouth. Over the past several years, hydroquinone has become a controversial skincare ingredient for topical use.
Hydroquinone msds material safety data sheet or sds, coa and coq, dossiers, brochures. Hydroquinone reference material extrasynthese, hydroquinone. Compared with unsubstituted hydroquinone, its higher solubility and increased potency at. Hydroquinone is linked to exogenous ochronosis, dermatitis and skin. Hydroquinone is a slight explosion hazard when exposed to heat. Hydroquinone was not safe for use in leaveon, nondrug cosmetic products. The dust my cause irritation of the nose, throat and upper respiratory tract. Show this safety data sheet to the doctor in attendance. Sigmaaldrich material safety data sheet date printed.
No warranty, express or implied, is made and qorpak assumes no liability resulting from the use of this msds. It is topically applied to treat melisma, freckles and senile lentigines. Sds of 2methylhydroquinone, safety data sheets, cas 95716. Mono tertbutylhydroquinone finds use primarily as a polymerization inhibitor and industrial antioxidant. Page 5 of 7 genotoxicity in vivo mouse oral micronucleus test laboratory experiments have shown mutagenic effects. Hydroquinone for cosmetic use is chemically synthesized. Clinical director, innovative skincare topical hydroquinone is used frequently throughout the world as a skin bleaching agent. Hydroquinone is a phenolic compound, which is naturally found in coffee, tea and wine. Carolina offers the highest quality kits for a handson approach within ap chemistry classrooms. Copying andor downloading of this information for the purpose of properly utilizing 3m products is allowed provided that. The user must determine suitability of this information for his application.
Chemical properties of hydroquinone cas 123319 download as pdf file download as excel file download as 2d mole file predict properties. Oh find msds or sds, a coa, data sheets and more information. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet. It is formed in large quantities by chemical reduction of benzoquinone. All products shown on this website are based on the eu portfolio pursuant to applicable eu regulations.
Extinguishing media protective equipment and wear selfcontained breathing apparatus and protective clothing to prevent contact with skin and eyes. Health, safety and environment, carestream health, inc. Download our flavors and fragrances catalog to view our entire product line. Choose from over 850 chemical products in chemical grades, sizes and concentrations to meet your needs. Jun 03, 2014 do not use hydroquinone together with benzoyl peroxide or resorcinol. Hydroquinone usp is a common ingredient found in temporary skin lightening or bleaching products. Material safety data sheet g5, industrial xray developerreplenisher part a subid. Safety data sheet vos2 1 product and company identification alliance group, inc. All spectrum chemical usp grade products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities.
Safety data sheet according to regulation ec no 19072006 page 1 of 12 loctite 406 sds no. Despite the controversy, its abundantly clear is that hydroquinone is a wellresearched ingredient, incredibly effective for its intended purpose, and that no other. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Hydroquinone cas no, 123319 is defined as the aromatic organic compound that conforms to the formula in figure 1.
The hydroquinone was extracted from samples by using 96% ethanol and was subjected to tlc analysis. View or download the hydroquinone msds material safety data sheet or sds for 822333 from milliporesigma. Here is the most complete msds list on the internet, and its free. Tertiary butylhydroquinone is a aromatic organic compound manufactured through chemical synthesis. Signs and symptoms of exposure absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Hot andor concentrated naoh can cause hydroquinone to decompose exothermically at elevated temperature. In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes.
The guide is intended to supplement training, material safety data sheets msdss, safety. Hydroquinone is an active allergen so repeated and prolonged exposure may cause skin sensitization. It is currently reported to function as an antioxidant, fragrance ingredient, hair colorant, reducing agent, and skin bleaching agent. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Looking for msds information regarding the chemicals in a commercial product or a material safety data sheet msds. Safety data sheet according to 29cfr19101200 and ghs rev. Material safety data sheet tertiary butylhydroquinonetbhq msds 1. Use of hydroquinone with any products containing benzoyl peroxide, hydrogen peroxide, or other peroxides may cause temporary staining of the skin. A dermatologists response to the 2006 federal register jacob levitt, md new york and hawthorne, new york recently, the us food and drug administration proposed a ban on overthecounter hydroquinone mainly on the basis of high absorption, reports of exogenous ochronosis in humans, and murine hepatic. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Material safety data sheet hydroquinone 2 ingestion. Sigmaaldrich material safety data sheet product name 4. Page 2 of 14 safety data sheet section 2 hazards identification continued label elements danger hazard statements harmful if swallowed causes skin irritation causes serious eye damage. Material safety data sheet hydroquinone 6 information in this msds is from available published sources and is believed to be accurate.
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